CVE-2026-54604OpenSlide: openslide_read_region() returns uninitialized memory with libtiff 4.7.1
Updated under an hour ago ()
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No exploitation reported and no EPSS estimate yet.
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OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.
- CVSS
- 5.3 MEDIUM (v4.0, CNA)CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N
- Weakness (CWE)
- CWE-758, CWE-908
- Known exploited
- Not in CISA's KEV catalog
- EPSS (exploitation in the next 30 days)
- Not loaded for this CVE
- Assigned by
- GitHub_M
- NVD analysis
- Awaiting Analysis
- Record last updated
- Sep 18, 2026
- First seen by InfoSec Signals
- Oct 9, 2026
Affected products
openslide openslide openslide:openslide (from the name) | before 4.0.1 | CNA record |
References
- https://github.com/openslide/openslide/security/advisories/GHSA-f734-jv98-5677x-refsource-confirm
- https://github.com/openslide/openslide-bin/issues/433x-refsource-misc
- https://github.com/openslide/openslide-bin/pull/436x-refsource-misc
- https://github.com/openslide/openslide/pull/706x-refsource-misc
- https://github.com/openslide/openslide/commit/a4f0fb0ec462edcea97ff22288f606ac6cd370f5x-refsource-misc
- https://github.com/openslide/openslide/releases/tag/v4.0.1x-refsource-misc
- https://gitlab.com/libtiff/libtiff/-/work_items/791x-refsource-misc
The CVE record on cve.org NVD's entry
The CVE record is authoritative. Products marked “from the name” were identified from the CNA's free-text names, not a CPE, and are matched less certainly. This product uses the NVD API but is not endorsed or certified by the NVD.