CVE-2026-31973SAMtools is a program for reading, manipulating and writing bioinformatics file formats.
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No exploitation reported and no EPSS estimate yet.
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SAMtools is a program for reading, manipulating and writing bioinformatics file formats. Starting in version 1.17, in the cram-size command, used to write information about how well CRAM files are compressed, a check to see if the `cram_decode_compression_header()` was missing. If the function returned an error, this could lead to a NULL pointer dereference. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
- CVSS
- 7.5 HIGH (v3.1, NVD)CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:N/I:N/A:H
- Weakness (CWE)
- CWE-476
- Known exploited
- Not in CISA's KEV catalog
- EPSS (exploitation in the next 30 days)
- Not loaded for this CVE
- Assigned by
- Not given
- NVD analysis
- Analyzed
- Record last updated
- Jun 17, 2026
- First seen by InfoSec Signals
- Oct 9, 2026
Affected products
samtools samtools samtools:samtools | from 1.17 through 1.21.1; from 1.22 before 1.22.2; 1.23 | NVD |
References
- https://github.com/samtools/samtools/commit/06fc2a219b3d7c94d3f412c09f6d1efd51199f2fpatch
- https://github.com/samtools/samtools/security/advisories/GHSA-x86f-q6fj-cm43vendor-advisory
- http://www.openwall.com/lists/oss-security/2026/03/18/12mailing-list, third-party-advisory
The CVE record on cve.org NVD's entry
The CVE record is authoritative. Products marked “from the name” were identified from the CNA's free-text names, not a CPE, and are matched less certainly. This product uses the NVD API but is not endorsed or certified by the NVD.