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High 8.1Published Mar 18, 2026

CVE-2026-31969HTSlib is a library for reading and writing bioinformatics file formats.

Updated under an hour ago ()

Does this affect you?

It affects htslib. Add what you run to find out whether that includes you.

No exploitation reported and no EPSS estimate yet.

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the `BYTE_ARRAY_STOP` method, an out-by-one error in the `cram_byte_array_stop_decode_char()` function check for a full output buffer could result in a single attacker-controlled byte being written beyond the end of a heap allocation. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

CVSS
8.1 HIGH (v3.1, NVD)CVSS:3.1/AV:N/AC:L/PR:N/UI:R/S:U/C:N/I:H/A:H
Weakness (CWE)
CWE-122, CWE-787
Known exploited
Not in CISA's KEV catalog
EPSS (exploitation in the next 30 days)
Not loaded for this CVE
Assigned by
Not given
NVD analysis
Analyzed
Record last updated
Jun 17, 2026
First seen by InfoSec Signals
Oct 9, 2026

Affected products

Affected products
htslib htslib
htslib:htslib
before 1.21.1; from 1.22 before 1.22.2; 1.23
NVD

References

  • patch
  • patch, vendor-advisory

The CVE record is authoritative. Products marked “from the name” were identified from the CNA's free-text names, not a CPE, and are matched less certainly. This product uses the NVD API but is not endorsed or certified by the NVD.

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