CVE-2026-31968HTSlib is a library for reading and writing bioinformatics file formats.

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. For the `VARINT` and `CONST` encodings, incomplete validation of the context in which the encodings were used could result in up to eight bytes being written beyond the end of a heap allocation, or up to eight bytes being written to the location of a one byte variable on the stack, possibly causing the values to adjacent variables to change unexpectedly. Depending on the data stream this could result either in a heap buffer overflow or a stack overflow. If a user opens a file crafted to exploit this issue it could lead to the program crashing, overwriting of data structures on the heap or stack in ways not expected by the program, or changing the control flow of the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

CVSS

8.1 HIGH (v3.1, NVD)CVSS:3.1/AV:N/AC:L/PR:N/UI:R/S:U/C:N/I:H/A:H

Weakness (CWE)

CWE-121, CWE-122, CWE-787, CWE-843

Known exploited

Not in CISA's KEV catalog

EPSS (exploitation in the next 30 days)

Not loaded for this CVE

Assigned by

Not given

NVD analysis

Analyzed

Record last updated

Jun 17, 2026

First seen by InfoSec Signals

Oct 9, 2026

The CVE record on cve.org · NVD's entry

The CVE record is authoritative. Products marked “from the name” were identified from the CNA's free-text names, not a CPE, and are matched less certainly. This product uses the NVD API but is not endorsed or certified by the NVD.