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High 7.8Published Sep 27, 2026

CVE-2026-100845MONAI before 1.6.0 Remote Code Execution via NumpyReader

Updated under an hour ago ()

Does this affect you?

It affects Project-MONAI MONAI and 1 other product. Add what you run to find out whether that includes you.

EPSS puts the chance of exploitation in the next 30 days at 0.14%, higher than 3% of scored CVEs.

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

CVSS
7.8 HIGH (v3.1, CNA)CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
Weakness (CWE)
CWE-502
Known exploited
Not in CISA's KEV catalog
EPSS (exploitation in the next 30 days)
0.14% (percentile 3)
Assigned by
VulnCheck
NVD analysis
Analyzed
Record last updated
Sep 28, 2026
First seen by InfoSec Signals
Oct 9, 2026

Affected products

Affected products
Project-MONAI MONAI
project_monai:monai (from the name)
before 1.6.0; 1.6.0 not affected
CNA record
project-monai monai
project-monai:monai
before 1.6.0
NVD

References

  • vendor-advisory, exploit
  • third-party-advisory

The CVE record is authoritative. Products marked “from the name” were identified from the CNA's free-text names, not a CPE, and are matched less certainly. This product uses the NVD API but is not endorsed or certified by the NVD.

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